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Table 2 Logistic regression analysis of predictors for clinical improvement in new-onset MG patients before COVID-19 outbreak

From: The characteristics of new-onset myasthenia gravis after COVID-19 outbreak: a cross-sectional study

Variables

Univariate analysis

Multivariate analysis

 

OR (95% CI)

P value

OR (95% CI)

P value

Baseline MG-ADL

1.720 (1.339, 2.211)

 < 0.001*

1.687 (1.282, 2.220)

 < 0.001*

Age at the onset

1.004 (0.986, 1.022)

0.697

0.987 (0.976, 1.008)

0.216

Vaccine

1.561 (0.666, 3.655)

0.305

  

Pyridostigmine

2.204 (0.589, 8.241)

0.240

1.422 (0.275, 7.365)

0.675

Immunosuppressant

1.616 (0.572, 4.567)

0.365

  

Prednisolone

2.442 (1.165, 5.117)

0.018*

1.667 (0.679, 4.091)

0.265

RNS-positive

1.925, (0.928, 3.396)

0.079

1.233 (0.506, 3.000)

0.645

Abnormal thymus

0.904 (0.436, 1.873)

0.786

  

Antibody status

1.171 (0.592, 2.316)

0.650

  

Smoking

1.561 (0.594, 4.105)

0.366

  

Season of onset

1.215 (0.840, 1.756)

0.301

1.187 (0.788, 1.786)

0.412

MGFA ≥ III

4.796 (1.388, 16.568)

0.013*

1.382 (0.256, 7.465)

0.707

Generalized MG

3.189 (1.515, 6.715)

0.002*

0.917 (0.312, 2.697)

0.875

Affect bulbar or respiratory muscles

4.037 (1.580, 10.312)

0.004*

1.558 (0.341, 6.160)

0.616

Infection rate

2.453 (0.525, 11.459)

0.254

  

MG duration

1.000 (0.976, 1.024)

0.972

  

Gender, male

1.179 (0.571, 2.432)

0.657

  
  1. Note: *P-value < 0.05 is significant. n = 165 (125 for clinical improvement, 40 for without clinical improvement)
  2. Abbreviations: MG Myasthenia gravis, MG-ADL MG activities of daily living profile, MGFA Myasthenia Gravis Foundation of America, RNS Repetitive nerve stimulation