Fig. 3
From: EIDD-2801 resists to infection and co-infection of SARS-CoV-2 and influenza virus

EIDD-2801 improves prognosis of mice co-infected with influenza virus and SARS-CoV-2. Mice co-infected with both H1N1-UI182 and Omicron BF.7 were monitored daily for clinical signs. A Body weight change of co-infected golden hamsters. B Representative images of lung tissue are presented, with photomicrographs showing histopathological changes (scale bars = 200 μm). C Lung index of hamsters 3 days after infection. D Histopathological scores of hamster lungs. E Viral RNA copy numbers of SARS-CoV-2 ORF1ab RNA in tracheas, lungs and turbinates. F Viral RNA copy numbers of SARS-CoV-2 ORF1ab RNA in nasal lavages. G Viral RNA copy numbers of H1N1 M gene in tracheas, lungs and turbinates. G Viral RNA copy numbers of H1N1 M gene in nasal lavages. Differences were considered significant at (**) 0.001 < P < 0.01, (***) P < 0.001