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Fig. 1 | Virology Journal

Fig. 1

From: Usutu virus NS4A induces autophagy and is targeted by the selective autophagy receptor p62/SQSTM1 for degradation

Fig. 1

The USUV NS4A interactome is enriched for autophagy related proteins. A Schematic representation of USUV NS4A structure. B Schematic overview of the workflow of the proximity labeling assay. C-E Gene ontology analysis of the USUV NS4A interactome to identify statistically enriched molecular functions (C), cellular components (D), and biological processes (E). F STRING network analysis of potential interaction partners of USUV NS4A as identified in the proximity screen involved in autophagy. Line thickness indicates the degree of confidence prediction of the interaction (ranging from 0.4 to 1). The interaction of SQSTM1/p62 (orange) with USUV NS4A was further validated in this study

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Virology Journal

ISSN: 1743-422X