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Fig. 1 | Virology Journal

Fig. 1

From: SARS-CoV-2 lineage-dependent temporal phylogenetic distribution and viral load in immunocompromised and immunocompetent individuals

Fig. 1

Whole-genome analysis and single mutation analysis (A) Multiple correspondence analysis shows no distinct mutation profile between controls and immunocompromised patients. Sequences form clusters according to their lineage and their similarities from one lineage to another, such as BA.2 and its sub-lineage BA.5 and BQ.1 (B). Single mutation analysis display on the volcano plot, showing three amino acid substitutions in the Spike protein and three substitutions in the M, ORF10 and NSP3 proteins. Substitutions S: R346K and NSP3:T127N are positively associated to NICs group and S: T95I, S:N764K, ORF10: L37F and M: Q19E are positively associated to immunocompromised patients group (C)

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