Clinical manifestation | Total n = 441 | IEI_I n = 115 | IEI_II n = 47 | IEI_III n = 102 | IEI_IV n = 26 | IEI_V n = 95 | IEI_VI n = 36 | Others a n = 18 | p value |
---|---|---|---|---|---|---|---|---|---|
 Cough | 314(71.20%) | 100(87.07%) | 32(68.09%) | 65(63.73%) | 15(59.26%) | 67(70.53%) | 22(61.11%) | 11(61.11%) | 0.001 |
 Enlarged lymph nodes | 264(59.86%) | 64(55.17%) | 23(48.94%) | 55(53.92%) | 17(62.96%) | 60(63.16%) | 31(86.11%) | 14(77.78%) | 0.006 |
 Abnormal liver function | 114(25.85%) | 44(37.93%) | 17(36.17%) | 11(10.78%) | 10(37.04%) | 21(22.11%) | 5(13.89%) | 6(33.33%) | <0.001 |
 Fever | 239(54.20%) | 69(60.37%) | 23(48.94%) | 38(37.25%) | 17(66.67%) | 59(62.11%) | 17(47.22%) | 14(77.78%) | 0.001 |
 Hepatomegaly | 145(32.88%) | 42(36.21%) | 10(21.28%) | 29(28.43%) | 11(40.74%) | 30(31.58%) | 16(44.44%) | 7(38.89%) | 0.263 |
 Retinitis | 38(8.62%) | 19(16.38%) | 6(12.77%) | 1(0.98%) | 1(7.41%) | 7(7.37%) | 1(2.78%) | 2(11.11%) | 0.002 |
 Splenomegaly | 131(29.71%) | 32(27.59%) | 9(19.15%) | 33(32.35%) | 9(33.33%) | 29(30.53%) | 14(38.89%) | 5(27.78%) | 0.571 |
 Diarrhea | 133(30.16%) | 50(43.10%) | 10(21.18%) | 17(16.67%) | 8(29.63%) | 32(33.68%) | 9(25.00%) | 7(38.89%) | 0.002 |
 Expectoration | 163(36.96%) | 48(41.38%) | 18(38.30%) | 40(39.22%) | 7(29.63%) | 34(35.79%) | 10(27.78%) | 5(27.78%) | 0.627 |
 Dysplasia | 39(8.84%) | 8(6.90%) | 7(14.89%) | 13(12.75%) | 3(11.11%) | 4(4.21%) | 2(5.56%) | 2(11.11%) | 0.245 |