Fig. 2
From: Multiple gene-deletion vaccinia virus Tiantan strain against mpox

Protective efficiency of TTVAC7 and TTVC5 in mice against VTT challenge. (A) Changes to the body weight of mice after VTT challenge. A remarkable weight loss could be observed in the model group. (B, C) Images of lung tissues, H&E staining, and H&E histological score (magnification of 20× and 63×). The residual virus of mice after VTT challenge were measured with a viral plaque formation assay. (D) The VTT titers of nose, trachea, and lung tissues in each group (ns, not significant, **p < 0.01, ##p < 0.01)