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Table 2 Kinetics of NAbs formation in bivalent HFRS inactive vaccine recipients as measured by standard HTNV (Strain 76–118) based FRNT or replication-competent rVSV-HTNV-GP based PRNT

From: Standardization, validation, and comparative evaluation of a convenient surrogate recombinant vesicular stomatitis virus plaque reduction test for quantification of Hantaan orthohantavirus (HTNV) neutralizing antibodies

Serum donor

Age at vaccination

Gender

Interval following vaccination (Month)

NAbs titer against rVSV-HTNV-GP (PRNT50)

NAbs titer against HTNV 76–118 strain (FRNT50)

Decimal

Log10

Decimal

Log10

Vaccinee #1

50

Female

1

1648

3.217

122.6

2.089

   

11

1407

3.148

18.69

1.272

   

22

917.3

2.963

80.87

1.908

   

35

1171

3.068

43.21

1.636

   

46

426.9

2.63

44.32

1.647

Vaccinee #2

59

Male

2

1948

3.29

292.5

2.466

   

17

111.6

2.048

36.24

1.559

   

22

598.9

2.777

87.46

1.942

   

46

225

2.352

99.11

1.996

   

57

339.5

2.531

120.5

2.081

Vaccinee #3

54

Female

1

105.6

2.024

72.31

1.859

   

8

426.4

2.63

59.22

1.772

   

22

33.56

1.526

30.13

1.479

   

34

21.54

1.333

25.52

1.407

   

47

29.18

1.465

17.88

1.252

Vaccinee #4

56

Female

1

1018

3.008

65.54

1.817

   

8

911.6

2.96

22

1.342

   

22

180

2.255

12.81

1.107

   

34

134

2.127

23.6

1.373

   

47

167

2.223

22.28

1.348

Vaccinee #5

39

Female

1

7602

3.881

216.9

2.336

   

8

3516

3.546

85.11

1.93

   

22

291.9

2.465

21.66

1.336

   

33

3460

3.539

66.26

1.821

   

46

1696

3.229

81.73

1.912